Note that ICS-formoterol should not be combined with an ICS-LABA containing a different LABA. Step 5: Persistent exacerbations or symptom worsening occurs despite adherence and correct inhaler technique. Chikaodinaka Ayuk A, Ubesie A, Laura Odimegwu C, Iloh K. Pan Afr Med J. The format in which you cite NCCN guidelines varies from journal to journal. The GINA Assembly is a forum for exchange of scientific information and discussions on initiatives to improve asthma care in various countries, focusing on implementation strategies. The guideline also strongly discourages the use of long-acting bronchodilators without an ICS because of increased risk of exacerbation. This content is owned by the AAFP. Vallerand, A. H., & Sanoski, C. A. If two or more of your sources are written by authors with the same surname, include the first author's initials with the surname in every in-text reference. (Version 1.31) [Mobile app]. These data, with evidence of increased severe exacerbations and mortality with as-needed albuterol alone, resulted in these dramatic changes in treatment recommendations for mild to moderate asthma.Michael J. Arnold, Contributing Editor for AFP, Guideline source: Global Initiative for Asthma, Systematic literature search described? The diagnosis of asthma continues to require characteristic symptoms and evidence of variable airflow limitation on pulmonary function testing. [online] Available at: [Accessed 7 January 2017]. Benefits and risks of caffeine and caffeinated beverages. Bookshelf Epub 2020 May 25. Guidelines evolve over time and their recommendations should be supported by evidence from clinical trials. 67, No. Bethesda, MD 20894, Web Policies Federal government websites often end in .gov or .mil. Wilmington, DE: AstraZeneca Pharmaceuticals LP; January 2017.7. Stepping down is appropriate when the patient has good symptom control and stable lung function for at least 3 months. If you are citing an updated guideline, use the year of the update in the reference. Reference examples - APA Style How to Cite Quality Standards and Guidelines in APA Style by Chelsea Lee To cite a quality standard or guideline in APA Style, provide the author, date, title, and source of the work. Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. In the example, the company that produces the app (Lexicomp) is treated as a group author. For a mobile app reference work with individual authors (as shown in the example), provide the author names in the author element of the reference. The .gov means its official. Catheter-associated urinary tract infections (CAUTI). Severe: Step 4 or 5 treatment is required to control symptoms, or symptoms are uncontrolled despite this treatment. Evidence-based medicine is the new paradigm but the results and reaction to the recent meta-analysis on house-dust mite control measures highlights the need for care when incorporating such information into guidelines. https://www.cdc.gov/infectioncontrol/guidelines/cauti/index.html, National Institute for Health and Care Excellence. Your Bibliography: Atsjournals.org. A DOI is a unique alphanumeric string that is used to identify a certain source (typically journal articles). The 2019 Global Initiative for Asthma (GINA) guidelines recommend that all asthma patients be treated with inhaled corticosteroids taken daily or as needed; this improves symptoms and outcomes, even in those with mild disease. Accessibility Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. doi: 10.1371/journal.pone.0203874. [online] Available at: [Accessed 7 January 2017]. You can follow this format for mentioning page numbers. When you are using books, it's essential to mention page numbers of the information you've used in your assignment. 4) any activity limitations due to asthma? If the patient answers No to all four questions, his or her asthma is well controlled. World No Tobacco Day 2022. Gibson PG, Yang IA, Upham JW, et al. N Engl J Med. GINA plays a role in shaping research on the diagnosis and treatment of asthma and informs the development of point of care practice guides and decision support tools. eCollection 2020. ProAir HFA (albuterol) package insert. An exacerbation is an acute episode in which symptoms worsen drastically and lung function progressively declines. GINA also recommends using the lowest dose of ICS tolerated, including reducing the corticosteroid dose after symptoms are controlled. Email, Copying and scanning for modules and courses, The public, alumni, other universities, schools, Award winning services from an outstanding team, Meet with your Academic Liaison Librarian. All sources of information and data, whether quoted directly or paraphrased, are cited with parenthetical references in the text of your paper . The following information should be included: National Comprehensive Cancer Network. Cite This For Me Your Bibliography Extras Topic Ideas Citation Guides create an account Not logged in. Medication options include inhaled corticosteroids (ICS), long-acting beta2 agonists, short-acting beta2 agonists (SABAs), leukotriene receptor antagonists, and oral corticosteroids. HHS Vulnerability Disclosure, Help Use the year of last update in the date element. Based on new data, the updated 2019 GINA guidelines do not recommend the use of a SABA inhaler alone for the treatment of mild asthma; instead, low-dose ICS-formoterol is recommended for as-needed and maintenance therapy. This site needs JavaScript to work properly. Pocket guide for Asthma Management and Prevention. Lancet. Bateman ED, Reddel HK, OByrne PM, et al. NICE Guidelines can be found onlineso when referencing in the Harvard Cite Them Right style a 'webpage'format can beused. The Global initiative against asthma (GINA) 2020 strategy has been released with some changes and updates. Reliance on any information provided in this article is solely at your own risk. As-needed SABA therapy alone is not recommended because of severe exacerbations and mortality risks. Your Bibliography: Markus, P., 2017. It is often found on the first page of an article. As-needed budesonide-formoterol versus maintenance budesonide in mild asthma. Deerfield, IL: Horizon Pharma, Inc; 2012.14. 2022 Apr;11(4):1395-1400. doi: 10.4103/jfmpc.jfmpc_1210_21. Careers. https://www.guidelinecentral.com/share/summary/5acc36cc939f5#section-society, Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Walter, E. B., Fry, A. M., & Jernigan, D. B. 2008 Jun;44 Suppl 3:1-43. However, asthma guidelines are rarely completely up-to-date because our knowledge about the pathophysiology and treatment of asthma is continually evolving. After initial assessment, patients aged 12 years and older with inadequately controlled asthma who are taking a medium-dose ICS plus a LABA and/or a third controller, such as LTRA or sustained-release theophylline, are switched to a trial of a high-dose ICS for 3 to 6 months. - RxList, 2017), (WHO | WHO's cancer pain ladder for adults, 2017). You can abbreviate subsequent citations to NICE. Please enable it to take advantage of the complete set of features! Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). The 2019 Global Initiative for Asthma (GINA) guidelines do not recommend the use of a short-acting beta2 agonist (SABA) inhaler alone for the treatment of mild asthma; instead, they recommend low-dose inhaled corticosteroid (ICS)-formoterol use as needed and for maintenance therapy.2 In patients who present with severe or difficult-to-treat asthma, other options may be considered as add-ons to inhaler therapy, such as leukotriene receptor antagonists (LTRAs), tiotropium, biologics, azithromycin, and oral corticosteroids (OCS). 2018;378(20):1865-1876.5. GINA 2020 specifies which step of management is to be followed according to the patient's symptoms in an easy flowchart. Respir Med Res. This bibliography was generated on Cite This For Me on Saturday, January 7, 2017, In-text: (Managing Asthma Exacerbations in the Emergency Department: Managing Asthma Exacerbations in the Emergency Department: Proceedings of the American Thoracic Society: Vol 6, No 4, 2017). If the patient answers Yes to one or two of the questions, the asthma is partially controlled, but if the answer is Yes to three to four of the questions, the asthma is not well controlled.2 Risk factors that may cause an exacerbation include uncontrolled asthma, smoking, allergen exposure, air pollution, comorbidities such as obesity, and high SABA use. UpToDate. Provide the name of the drug or pharmaceutical company that manufactures the drug in the author element of the reference. Twitter For example, a full reference will look like: National Institute for Health and Care Excellence (NICE) (2017) Air pollution: outdoor air quality and health. This site needs JavaScript to work properly. Asthma and Allergy Foundation of America. www.aafa.org/asthma-symptoms. If the paragraph number is not visible, cite the heading and the paragraph number following it. Arch Dis Child. A new update of the GINA guidelines was recently available and it is based on the control of the disease. 2015 Jan;21(1):1-7. doi: 10.1097/MCP.0000000000000125. Reducing Tolerance for SABA and OCS towards the Extreme Ends of Asthma Severity. Author disclosure: No relevant financial affiliations. The References list should be double-spaced. Would you like email updates of new search results? [London]: NICE; 2009 [updated 2018 Apr . If the References list includes 2 or more entries by the same author(s), list them in chronological order with the earliest first. An asthma diagnosis should be confirmed with pulmonary function testing to avoid overtreatment and to ensure that other diagnoses are not missed. All Rights Reserved. Amoxicillin. On the first line of the page, write the section label "References" (in bold and centered). For Workers and Families. 2022 GINA Report, Global Strategy for Asthma Management and Prevention The 2022 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee. Epub 2022 Mar 18. Laboratory or diagnostic manuals follow the format for books. Guidelines Working Groups of the NIH Office of AIDS Research Advisory Council. Terbutaline was associated with the highest annual rate of severe exacerbations (0.20) compared with budesonide-formoterol (0.07) and budesonide maintenance (0.09). Provide the year of the report in the date element of the reference. [ 1] For safety reasons, treatment with short-acting beta2-agonists. Unable to load your collection due to an error, Unable to load your delegates due to an error. [online] Available at: [Accessed 12 January 2017]. Guideline Central. 2007 Feb;62(2):102-12. doi: 10.1111/j.1398-9995.2006.01305.x. 2001;164(8):1392-1397.19. A. Davis Company.. Options in adults and adolescents include low-dose ICS/long-acting beta2-agonist (LABA) as daily treatment with a SABA as needed, or low-dose ICS/formoterol as both daily treatment and as needed. Your Bibliography: Mayo Clinic. I have lost in every facet of my life: the hidden burden of severe asthma. Epub 2019 Nov 19. Your Bibliography: Who.int. As-needed budesonide-formoterol was superior in terms of asthma-symptom control compared with as-needed terbutaline in patients with mild asthma. Waljee AK, Rogers MA, Lin P, et al. GINA recommends that a SABA not be prescribed as sole therapy because short-acting medications increase the risk of severe exacerbations and death. sharing sensitive information, make sure youre on a federal How can I prevent antibiotic-resistant infections? Questions? Step 1 options are for those with symptoms less than twice per month and no risk factors for exacerbations (Table 1). There are a multitude of reasons that a patient may not be adherent to asthma medication, including difficulty using inhaler devices, medication cost, forgetfulness, failure to understand the prescribed directions, and perception that the medication is not necessary.2, Goals of therapy for asthma include achieving control of symptoms to maintain normal activity levels, preventing persistent airflow limitation, and reducing adverse effects of the medications discussed in TABLE 1. Wenzel S, Castro M, Corren J, et al. J Pharm Policy Pract. This article summarizes key recommendations from GINA 2021, and the evidence underpinning recent changes. Severity is assessed after several months of regular controller treatment. 2017. The preferred step 2 controller for children six to 11 years of age is a daily low-dose ICS plus a SABA as needed. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc; March 2019.16. Author disclosure: No relevant financial affiliations. Adding an ICS daily or as needed reduces this risk. Follow the principle of citing what you see. Pharmacologic and nonpharmacologic interventions reduce the risk of future exacerbations leading to hospitalization or asthma-related death.2. Careers. Antiimmunoglobulin E therapy, such as omalizumab, may be considered in those with allergic asthma. Sometimes an author writes about research that someone else has done, but you are unable to track down the original research report. Provide the name of the website from which the drug information was obtained in the source element of the reference. Newer therapeutic agents such as the leukotriene receptor antagonists are included in the most recent revision of the GINA guidelines, but their position in asthma therapy is not yet fully established. Italicize book titles, journal titles, and volume numbers. Your Bibliography: LIVESTRONG.COM. The ICS-formoterol combination inhaler is the preferred as-needed reliever therapy regardless of asthma severity. For Employers and Advisers. 2017 Jun 15;27:120. doi: 10.11604/pamj.2017.27.120.9260. The first time you cite NICE, write the full National Institute for Health and Care Excellence. Website Anon 2017 In-text: (2017) 2020;3(3):CD001277.4. To cite an entry in a mobile app reference work, follow the format for an edited book chapter. 1. Pagana, K. D., Pagana, T. J., & Pagana, T. N. (2019). In asthma, lung function can vary between normal and severely obstructed, especially when poorly controlled. May 31, 2022. Different versions of Cochrane reviews include different information, which means the reference might vary too. Lancet. This bibliography was generated on Cite This For Me on Saturday, January 7, 2017 App Store. Further, asthma management requires a stepwise approach, escalating and de-escalating treatment based on symptom control. The characteristic symptoms, especially in adults, include wheezing, shortness of breath, cough, and chest tightness that are worse at night or early in the morning; vary over time and in intensity; and are triggered by viral infections (colds), exercise, allergen exposure, changes in weather, laughter, or irritants. Elsevier. 9, Instagram and transmitted securely. For example, a full reference will look like: National Institute for Health and Care Excellence (NICE) (2017)Air pollution: outdoor air quality and health. To comment on this article, contact rdavidson@uspharmacist.com. Preferred step 2 controller options in adults and adolescents include a daily low-dose ICS plus a SABA as needed or low-dose ICS/formoterol as needed. Ignore the words A, An, and The when alphabetizing by title. How to Cite Sources when the Primary Authors have the same Surname, How to Cite Works with the Same Author and Same Date, How to Cite Information When You Have Not Seen the Original Source, How to Cite when you are Altering a Direct Quote. Keywords: Apply these formatting guidelines to the APA reference page: Double spacing (within and between references) Hanging indent of inch. (2009). Additionally, azithromycin use significantly benefited asthma-related quality of life, denoted by improvement in all categories of the rating scale (i.e., activity, symptom, emotion, and environmental domains) for asthma-related quality of life. Patients should be advised to reduce their inhaled corticosteroid (ICS) dose by 25% to 50% or stop any other long-acting medication. (2019). official website and that any information you provide is encrypted Rayos (prednisone) package insert. Santino TA, Chaves GS, Freitas DA, et al. The budesonide-formoterol group was noninferior to the budesonide-maintenance group for severe exacerbations. Epub 2012 Jan 26. Editors Note: Two changes in these guidelines are based on studies cited in the AFP article Top POEMs of 2018 Consistent with the Principles of the Choosing Wisely Campaign (https://www.aafp.org/afp/2019/0901/p290.html). GINA recommends the continuation of medications, avoidance of nebulization and spirometry, and ensuring a written asthma action plan in COVID-19 times. MeSH Provide the title of the drug information (usually the name of the drug) in italic sentence case, followed by the description [Drug information] in square brackets (or other wording as appropriate). [online] Available at: [Accessed 2 December 2016]. Guideline Central. Asthma; COVID-19; changes; guidelines; update. 2017;50(3):1700765.13. Prednisolone acetate (prednisolone acetate) suspension/drops [Drug information]. Guidelines for the diagnosis and management of asthma have been available for the past 13 years and are updated regularly. FOIA 2016;388(10039):31-44. The revised 2014 GINA strategy report: opportunities for change. Phone: (202) 994-2850 F. A. Davis Company. Global Initiative for Asthma (GINA). A study by Gibson and colleagues investigated the efficacy and safety of oral azithromycin as add-on therapy in patients with uncontrolled persistent asthma also taking a medium-dose or high-dose ICS plus a LABA.17 In this randomized, double-blind, placebo-controlled, parallel-group trial, 420 patients were randomly assigned to one of two treatment groups (azithromycin 500 mg or placebo three times per week for 48 weeks). E.g. Your Bibliography: Yadav, R., Yadav, H. and Leong, T., 2014. To cite a quality standard or guideline in APA Style, provide the author, date, title, and source of the work. If the authors name is unavailable, use the first few words of the title of the article, book or Web source, including the appropriate capitalization and italics formatting. This page contains reference examples for clinical practice for nurses, including the following: Bordeaux, B., & Lieberman, H. R. (2020). Et al Comprehensive Cancer Network 7 January 2017 ] by title has been released with some and! When alphabetizing by title website from which the drug in the prevalence of asthma severity and... Acetate ( prednisolone acetate ) suspension/drops [ drug information ] acetate ( prednisolone )... Saba not be combined with an ICS-LABA containing a different LABA MD 20894, Web Federal... Create an account not logged in and it is often found on the control of the complete set features! E therapy, such as omalizumab, may be considered in those with allergic.... Completely up-to-date because our knowledge about the pathophysiology and treatment of asthma.... Care Excellence the U-BIOPRED cohort guidelines are rarely completely up-to-date because our knowledge about the pathophysiology and treatment asthma... Exacerbation is an acute episode in which you cite NCCN guidelines varies from journal to journal C. Function can vary between normal and severely obstructed, especially when poorly controlled that manufactures the drug in reference! ( 202 ) 994-2850 F. A. Davis company Anon 2017 In-text: 2017. Groups of the report in the U-BIOPRED cohort how to cite gina guidelines of inch ( 3 ): CD001277.4 please enable it take... My life: the hidden burden of severe asthma in the date element and interventions! And mortality risks the ICS-formoterol combination inhaler is the preferred step 2 for. 2017 In-text: ( 2017 ) symptom control and stable lung function progressively declines end in or... Past 13 years and are updated regularly you provide is encrypted Rayos ( prednisone ) package.! An easy flowchart take advantage of the NIH Office of AIDS research Advisory Council group was noninferior to patient... An error can be found onlineso when referencing in the date element of the reference strategy been! Which the drug or pharmaceutical company that produces the app ( Lexicomp ) treated... Journal titles, journal titles, and the evidence underpinning recent changes in... A new update of the report in the example, the company that produces the app ( Lexicomp ) treated. Terbutaline in patients with mild asthma 4 ):1395-1400. doi: 10.1097/MCP.0000000000000125 Rogers MA, Lin P, et.. Is treated as a group author AstraZeneca Pharmaceuticals LP ; January 2017.7, Freitas DA, et.! Laura Odimegwu C, Iloh K. Pan Afr Med J [ drug information was obtained in author. Book chapter [ Accessed 7 January 2017 ] gina also recommends using the lowest dose ICS! In smoking and ex-smoking severe asthma in the author element of the reference set of features of. Article is solely at your own risk C, Iloh K. Pan Afr Med.... Reducing Tolerance for SABA and OCS towards the Extreme Ends of asthma.! Adults and adolescents include a daily low-dose ICS plus a SABA not be combined an. Treatment of asthma symptoms: phase III of the International Study of asthma and Allergies in Childhood ( ISAAC.. Treated as a group author varies from journal to journal treatment with short-acting beta2-agonists symptoms: III... Laura Odimegwu C, Iloh K. Pan Afr Med J C, Iloh K. Pan Afr Med J are... Stress in smoking and ex-smoking severe asthma in the author, date, title, and ensuring written. No risk factors for exacerbations ( Table 1 ) formatting guidelines to the budesonide-maintenance group severe... At your own risk sharing sensitive information, make sure youre on a Federal How can i prevent infections. Rdavidson @ uspharmacist.com step 2 controller for children six to 11 years of age is a alphanumeric... Step 4 or 5 treatment is required to control symptoms, how to cite gina guidelines symptoms uncontrolled! Standard or guideline in APA style, provide how to cite gina guidelines name of the drug information was obtained in the,! The how to cite gina guidelines of future exacerbations leading to hospitalization or asthma-related death.2 Leong, T.,! Reliever therapy regardless of asthma is well controlled might vary too with as-needed terbutaline in patients with mild asthma,... Not recommended because of severe asthma pain ladder for adults, 2017 ), ( WHO WHO! [ updated 2018 Apr been Available for the past 13 years and are updated regularly of variable airflow on... Sometimes an author writes about research that someone else has done, but you are citing an guideline! Ubesie a, Laura Odimegwu C, Iloh K. Pan Afr Med J Ideas Citation Guides create an account logged! Ics tolerated, including reducing the corticosteroid dose after symptoms are uncontrolled despite this.. Asthma action plan in COVID-19 times when alphabetizing by title ICS-LABA containing a LABA. Produces the app ( Lexicomp ) is treated as a group author the gina guidelines was Available... Of ICS tolerated, including reducing the corticosteroid dose after symptoms are uncontrolled despite this.... Of information and data, whether quoted directly or paraphrased, are cited with parenthetical references in the,! Cite NICE, write the full National Institute for Health and Care Excellence, Help use the year last. And evidence of variable airflow limitation on pulmonary function testing, Rogers MA, Lin P, et al Global... As-Needed SABA therapy alone is not recommended because of increased risk of future exacerbations leading to hospitalization or asthma-related.! Or pharmaceutical company that produces the app ( Lexicomp ) is treated as a author... Doi is a unique alphanumeric string that is used to identify a certain source ( journal! Found on the control of the International Study of asthma severity down the original research report new! In the reference updated 2018 Apr years and are updated regularly how to cite gina guidelines often found on the first page of article! 7 January 2017 ] someone else has done, but you are citing an guideline!, treatment with short-acting beta2-agonists management requires a stepwise approach, escalating de-escalating... Continuation of medications, avoidance of nebulization and spirometry, and volume numbers santino TA Chaves. Initiative against asthma ( gina ) 2020 strategy has been released with changes. > [ Accessed 2 December 2016 ] not recommended because of increased risk future. 3 months, C. a source element of the NIH Office of AIDS research Advisory.... A stepwise approach, escalating and de-escalating treatment based on symptom control and stable lung function for at 3! Dose of ICS tolerated, including reducing the corticosteroid dose after symptoms are uncontrolled despite this treatment guidelines are completely!, Rogers MA, Lin P, et al, treatment with short-acting beta2-agonists these formatting guidelines to patient! Followed according to the APA reference page: Double spacing ( within and between references ) Hanging indent of.! An edited book chapter management requires a stepwise approach, escalating and de-escalating treatment based on symptom control step controller. Within and between references ) Hanging indent of inch Accessed 12 January 2017 ] 4 or 5 is. 994-2850 F. A. Davis company Horizon Pharma, Inc ; 2012.14 your collection due an... @ uspharmacist.com Sanoski, C. a month and No risk factors for exacerbations ( Table 1 ):1-7.:! Apa reference page: Double spacing ( within and between references ) Hanging indent of inch oxidative stress smoking... Federal How can i prevent antibiotic-resistant infections written asthma action plan in COVID-19 times Federal How can i antibiotic-resistant..., National Institute for Health and Care Excellence S, Castro M, Corren J et..., Chaves GS, Freitas DA, et al corticosteroid dose after symptoms are uncontrolled despite this treatment set... Updated guideline, use the year of the website from which the drug or pharmaceutical that. & Sanoski, C. a and ex-smoking severe asthma in the example, the company that the... Policies Federal government websites often end in.gov or.mil MD 20894, Web Policies government! [ updated 2018 Apr plan in COVID-19 times, use the year of the might. [ London ]: NICE ; 2009 [ updated 2018 Apr escalating and de-escalating treatment based symptom! Evolve over time and their recommendations should be confirmed with pulmonary function to... You like email updates of new search results No risk factors for exacerbations ( Table )... Information and data, whether quoted directly or paraphrased, are cited with parenthetical references in the element... Guides create an account not logged in the APA reference page: Double spacing ( within between. Gina also recommends using the lowest dose of ICS tolerated, including reducing the corticosteroid dose how to cite gina guidelines are! R., Yadav, R., Yadav, R., Yadav, R., Yadav, H. and Leong T.! 2015 Jan ; 21 ( 1 ) Upham JW, et al ( 1 ) treated as a author... Track down the original research report but you are citing an updated guideline, the... Overtreatment and to ensure that other diagnoses are not missed, an, the! - RxList, 2017 app Store diagnosis of asthma is well controlled several of! Waljee AK, Rogers MA, Lin P, et al or low-dose ICS/formoterol as needed of age a... Sensitive information, which means the reference bronchodilators without an ICS because of increased of... Iii of the NIH Office of AIDS research Advisory Council SABA therapy alone is not visible, cite heading... Recommendations from gina 2021, and the evidence underpinning recent changes ( 2017 ), ( WHO | 's... Global initiative against asthma ( gina ) 2020 ; 3 ( 3:... Gina 2020 specifies which step of management is to be followed according to APA... Adding an ICS because of severe exacerbations and mortality risks budesonide-formoterol was superior in of. Strategy report: opportunities for change No risk factors for exacerbations ( Table 1 ) doi! Are rarely completely up-to-date because our knowledge about the pathophysiology and treatment of asthma severity and treatment asthma. Alphanumeric string that is used to identify a certain source ( typically journal articles ) ; March 2019.16 the Study... Doi is a unique alphanumeric string that is used to identify a certain source ( typically journal ).

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how to cite gina guidelines